Phase 1

• First time in humans
• Pharmacokinetics
• Pharmacodynamics
• Radiolabelled compounds
• Positron emission tomography
• Microdosing
• Drug interactions
• Biotechnology
• Bridging studies
• Special groups:
  • elderly
  • post-menopausal
  • genetic polymorphisms
  

Types of study 2005–2009 (n=109*)
* 35% = FTIM