We offer a state-of-the-art service for all kinds of trials that require the administration of a radionuclide. We have our own ARSAC (Administration of Radioactive Substances Advisory Committee) licence holder with more than 30 years’ experience of the clinical use of radiolabelled substances, and HMR has been executing trials of radiolabelled materials successfully since the company was founded.
Absorption, Distribution, Metabolism, Elimination (ADME)
Our ADME trials involve mainly IMP labelled with 14C (carbon-14), but we also have plenty of experience with radionuclides such as 125I (iodine-125) and 3H (tritium). Unusually, we’ve also worked with the stable isotope 2H (deuterium). In all of our 50 or so ADME trials, we’ve invariably succeeded in recovering nearly all the administered dose of radioactivity. That immaculate record is a reflection of our attention to detail, and our dedicated efforts to ensure that all our faecal and urine collections are 100% complete.