EEG

Since 1993, HMR has completed around 900 trials, over 200 of which involved compounds with CNS activity. Many of the trials were first-in-human.

We have experience of a wide variety of procedures to assess novel CNS compounds, including electroencephalography (EEG).

EEG electrodes are applied to specific positions on the scalp, to measure electrical signals propagating within the brain.   EEG is often done alongside measurements of signals from the eyes (electrooculography, EOG) and muscles (electromyography, EMG).

Analysis of EEG allows the assessment of neurological/cognitive state and function.

At HMR, we have a consistent record of producing high quality EEG data.  Our EEG facilities and expertise include

  • Facilities – 8 multipurpose, soundproof rooms
  • Staff – a dedicated team of specially trained staff, including an Advanced Procedures Lead and Neurophysiological Procedures Specialist who coordinate our EEG facilities. All staff who do EEG procedures receive rigorous training in EEG techniques, in addition to trial-specific training
  • Experience – we’ve worked with several expert suppliers, over the years.  We’ve also used  different systems for EEG recording, including caps and direct electrode placement, as well as tests involving the recording of potentials related to stimuli such as sound tones. Some of our trials have used photostimulation as a way of excluding subjects who might have epilepsy.  Finally, we’ve also worked with patients with mental health problems.