overview

General

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Purpose-designed clinical pharmacology unit on 4 floors, close to Central Middlesex Hospital – an ideal environment for trials of new medicines –

  • 145 beds in 3 wards
  • Specialist procedure rooms – allergy, endoscopy, cognitive function
  • Self-contained suites for sleep trials
  • Central monitoring
  • ECG telemetry
  • Urine processing labs, with integrated toilets
  • Facilities for handling radioactivity
  • Separate clinical and laboratory areas for trials of ‘light label’ and conventional doses of radionuclide
  • Dedicated outpatient unit
  • Designated facilities for monitors and auditors

Emergencies

Prudence and expertise have prevented any emergencies in the past – we do a comprehensive risk assessment of every trial – but, just in case –

  • Emergency alarms throughout
  • Resuscitation team 24/7 and resident physician
  • Rapid patient evacuation
  • Close to hospital acute services
  • Regular emergency scenario training
  • Clinical attachment of HMR physicians to ICU
  • Approved by Resuscitation Council for ILS training

Equipment

Cardiovascular

  • 52 SpaceLabs Ultraview bedside monitors with ECG, Sp02, NIBP recording
  • 24 SpaceLabs ECG telemetry units
  • 31 12-lead ECG machines
  • 50 Holter monitors
  • 25 SpaceLabs ambulatory BP recorders
  • USCOM blood velocity monitor

Metabolic & renal

  • 5 Nova Glucometers
  • 3 i-STAT analysers, Abbott Diagnostics

Respiratory

  • 3 Fujinon 530 Series Video Bronchoscopes
  • 3 Mefar dosimeters
  • Complete pulmonary laboratory, Morgan Medical
  • Jaeger exhaled NO monitor
  • 3 ‘Gold Standard’ Vitalograph spirometers
  • 8 MicroMedical Superspiro SU6000
  • MicroMedical MicroLab
  • 2 acoustic rhinometers, GM Instruments AR1

Neurological

  • 2 EEG machines – Walther Graphtek PL-270-N
  • Embla N7000 polysomnography system with connector units for EEG, EOG, ECG and EMG, and sensors for oximetry, respiratory effort, body position, nasal cannula, thermistor, and snoring

Gastrointestinal

  • 21 ambulatory pH monitors, Flexilog, Oakfield Instruments Ltd 2020
  • 3 Fujinon 530 Series gastroscopes

Ultrasound imaging

  • Siemens Sonoline Prima SLC

Pharmacy

  • 2 aseptic manufacturing suites
  • Radiopharmacy aseptic suite
  • QC of radiolabelled IMP by liquid scintillation counting
  • 2 dedicated non-sterile manufacturing suites
  • Continuous environmental monitoring, with integrated alarm
  • Secure, temperature-controlled storage
  • MHRA licence to manufacture IMPs and Specials
  • Home Office licence to supply and possess controlled drugs
  • Registered with the General Pharmaceutical Council

The Pharmacy has its own dedicated website.

Laboratory

  • Pneumatic tube for instant sample transfer from wards and outpatients
  • Robotic sample handling – centrifugation, level sensing, capping, aliquotting, labelling, sorting & storage
  • Separate suites for light-sensitive samples and radioimmunoassay
  • Backup analysers to ensure continuous service
  • Seamless LIMS, from sample collection to reporting

The laboratory has its own dedicated website.

     

Sample storage

  • Secure sample storage at 4°C, –20°C and –80°C
  • Continuous temperature monitoring
  • Integrated alarm and 24/7 cover

Archive

  • Secure, temperature-controlled, document store – on site
  • Long-term archive at Iron Mountain with next day delivery – faster options available
  • Dedicated archivist